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Aaron Lewis
Aaron Lewis

76 Followers

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René Descartes and Information Asymmetry

My Reflections on "Meditations on First Philosophy" — The first thought associated with René Descartes is his quote, "I think therefore I am". Like the work of most musicians the best songs are not the hit singles but the ones found deeper in the album. …

4 min read

René Descartes and Information Asymmetry
René Descartes and Information Asymmetry

4 min read


Pinned

David Hume on Motivation and Religion

David Hume was an 18th century Scottish philosopher who was best known for his skepticism and empiricism — using experience and observation to inform philosophy. …

5 min read

David Hume on Motivation and Religion
David Hume on Motivation and Religion

5 min read


Pinned

3 Actionable Takeaways from Nietzsche’s Philosophy

One of the most profound thinkers of the last 2 centuries — Friedrich Nietzsche is one of the most influential philosophers of the last 200 centuries. His work investigates many aspects of the human condition — our motivations, thought processes, and goals. …

6 min read

3 Actionable Takeaways from Nietzsche’s Philosophy
3 Actionable Takeaways from Nietzsche’s Philosophy

6 min read


Published in Towards Data Science

·Pinned

Examining the Horvath Clock and the Statistical Method Behind it

How to find Biological Age from DNA Methylation Data — Imagine you are a researcher working in a lab to create an anti-aging pill. After months of researching different anti-aging supplements that historical groups have used you find a suitable intervention. The question now becomes how do you prove the intervention actually inhibits aging? In clinical trials, you can’t wait…

Data Science

7 min read

Examining the Horvath Clock and the Significance of Biological Age
Examining the Horvath Clock and the Significance of Biological Age
Data Science

7 min read


Pinned

Sirtuins and the Information Theory of Aging: A Key Piece in the Longevity Puzzle

Analyzing Sirtuins Impact on the Epigenome and Activation Pathways — My younger brother just finished the second book in the Harry Potter series. As some of you may remember (spoiler alert), the book spectacularly ends with Harry destroying the diary of Voldemort in the Chamber of Secrets. Inside the diary was a piece of Voldemorts soul — a “Horcrux” in…

Aging

14 min read

Sirtuins and the Information Theory of Aging: A Key Piece in the Longevity Puzzle
Sirtuins and the Information Theory of Aging: A Key Piece in the Longevity Puzzle
Aging

14 min read


Published in The Shadow

·Jan 25, 2021

What is the Root Cause of Plastic Pollution?

Examining the Value Chain of Plastic — Over 8 million metric tons of plastic are leaked into the ocean every year [Geyer]. That is equivalent to a garbage truck full of plastic being dumped into the ocean every minute. Projections estimate that plastic will outweigh fish in the ocean by 2050[WE Forum]. Why is this happening? How…

Plastic

13 min read

What is the Root Cause to Plastic Pollution?
What is the Root Cause to Plastic Pollution?
Plastic

13 min read


May 28, 2020

Stem Cells: A Key Integrative Hallmark of Aging

There are a number of theories that delve into the question — why do we age? Among the most popular theories is the stem cell theory of aging. The Stem Cell Theory of Aging argues that as we age our stem cells lose the ability to replenish and maintain tissues…

3 min read

Stem Cells: A Key Integrative Hallmark of Aging
Stem Cells: A Key Integrative Hallmark of Aging

3 min read


Published in The Startup

·May 18, 2020

Machine Learning X Drug Discovery : The Nexus of Computational Biology

On average it takes 10–20 years to develop a drug and costs 0.5 to 2.6 billion dollars 🤯. Drugs that do pass the pre-clinical trials phase have a success rate in clinical trials of only 6.2%. That is the worst part. …

Drug Development

5 min read

Machine Learning X Drug Discovery : The Nexus of Computational Biology
Machine Learning X Drug Discovery : The Nexus of Computational Biology
Drug Development

5 min read


May 9, 2020

Metformin, AMPK, and Aging

Nir Barzilai and the TAME study that has major implications for longevity — The key to longevity is balance. After reading the paper Hallmarks of Aging, which I would say is the hallmark paper of longevity, that was my main takeaway. For the majority of the therapies, whether it came down to stem cell repletion, senescent cell eradication, or inhibition of mTOR, the…

Aging

5 min read

Metformin, AMPK, and Aging
Metformin, AMPK, and Aging
Aging

5 min read


May 7, 2020

Senolytics and Senescent Cells’ Huge Potential Within Longevity

Last week I attended a conference called Longevity2020 where some of the top researchers and entrepreneurs gave talks on their latest pieces of work. One talk however, stood out to me for how “against the grain” its topic was. The talk was given by Reason (yes that is his name)…

Senescent Cells

5 min read

Senolytics and Senescent Cells’ Huge Potential Within Longevity
Senolytics and Senescent Cells’ Huge Potential Within Longevity
Senescent Cells

5 min read

Aaron Lewis

Aaron Lewis

76 Followers

17 year-old AI and human longevity enthusiast

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